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Articles (103)
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A comparative study on possible calcium antagonistic properties of indapamide and other drugs potentially interfering with calcium transport in isolated vascular smooth muscle

Dick J. De Wildt, Feddo C. Hillen

Journal:

European Journal of Pharmacology

Année:

1984

Langue:

english

Fichier:

PDF, 692 KB

english, 1984

Analgesia-Sedation in PICU and Neurological Outcome

van Zellem, Lennart, Utens, Elisabeth M., de Wildt, Saskia N., Vet, Nienke J., Tibboel, Dick, Buysse, Corinne

Journal:

Pediatric Critical Care Medicine

Année:

2014

Langue:

english

Fichier:

PDF, 467 KB

english, 2014

Advanced cancer pain: the search for genetic factors correlated with interindividual variability in opioid requirement

Matic, Maja, Jongen, Joost LM, Elens, Laure, de Wildt, Saskia N, Tibboel, Dick, Sillevis Smitt, Peter AE, van Schaik, Ron HN

Journal:

Pharmacogenomics

Année:

2017

Langue:

english

Fichier:

PDF, 1.06 MB

english, 2017

Monitoring Haloperidol Plasma Concentration and Associated Adverse Events in Critically Ill Children With Delirium

Slooff, Valerie D., van den Dungen, Desley K., van Beusekom, Babette S., Jessurun, Naomi, Ista, Erwin, Tibboel, Dick, de Wildt, Saskia N.

Journal:

Pediatric Critical Care Medicine

Année:

2017

Langue:

english

Fichier:

PDF, 106 KB

english, 2017

Enteral Acetaminophen Bioavailability in Pediatric Intensive Care Patients Determined With an Oral Microtracer and Pharmacokinetic Modeling to Optimize Dosing

Kleiber, Niina, Calvier, Elisa, Mooij, Miriam G., Krekels, Elke H. J., Vaes, Wouter H. J., Tibboel, Dick, Knibbe, Catherijne A. J., de Wildt, Saskia N.

Journal:

Critical Care Medicine

Année:

2019

Fichier:

PDF, 251 KB

2019

OPRM1 and COMT polymorphisms: implications on postoperative acute, chronic and experimental pain after cardiac surgery

Matic, Maja, de Hoogd, Sjoerd, de Wildt, Saskia N, Tibboel, Dick, Knibbe, Catherijne AJ, van Schaik, Ron HN

Journal:

Pharmacogenomics

Année:

2020

Fichier:

PDF, 444 KB

2020

Toxic doses of rac-, (−)-(S)- and (+)-(R)-propranolol in rats and rabbits

Arthur E. Toet, Anton Van De Kuil, Wim Vleeming, Johan Wemer, Wihelmina Bode, Jan Meulenbelt, Dick J. De Wildt

Journal:

Chirality

Année:

1996

Langue:

english

Fichier:

PDF, 719 KB

english, 1996

Toxicokinetics of a single intravenous dose of rac-propranolol versus optically pure propranolol in the rat

Wilhelmina Bode, Arthur E. Toet, Alida A. M. Stolker, Leendert A. Van Ginkel, Kees Groen, Johan Wemer, Dick J. De Wildt

Journal:

Chirality

Année:

1995

Langue:

english

Fichier:

PDF, 730 KB

english, 1995

Letters to the Editor

Dirk HG Versteeg, Dick J De Wildt

Journal:

Clinical and Experimental Pharmacology and Physiology

Année:

2003

Langue:

english

Fichier:

PDF, 15 KB

english, 2003

Different cardiovascular profiles of three melanocortins in conscious rats; evidence for antagonism between γ2-MSH and ACTH-(1–24)

Patricia Van Bergen, Jeroen A. Kleijne, Dick J. De Wildt, Dirk H. G. Versteeg

Journal:

British Journal of Pharmacology

Année:

1997

Langue:

english

Fichier:

PDF, 369 KB

english, 1997

Middle Cerebral Artery Occlusion in Wistar and Fischer-344 Rats: Functional and Morphological Assessment of the Model

Herz, Richard C. G., Jonker, Marcel, Verheul, Hieronymus B., Hillen, Berend, Versteeg, Dirk H. G., de Wildt, Dick J.

Journal:

Journal of Cerebral Blood Flow and Metabolism

Année:

1996

Langue:

english

Fichier:

PDF, 660 KB

english, 1996

Differences in striatal extracellular amino acid concentrations between wistar and fischer 344 rats after middle cerebral artery occlusion

Richard C.G. Herz, Pieter J. Gaillard, Dick J. de Wildt, Dirk H.G. Versteeg

Journal:

Brain Research

Année:

1996

Langue:

english

Fichier:

PDF, 993 KB

english, 1996

Distribution of Lys-γ2-melanocyte-stimulating hormone-(Lys-γ2-MSH)-like immunoreactivity in neuronal elements in the brain and peripheral tissues of the rat

Mariann Fodor, Arja Sluiter, Ank Frankhuijzen-Sierevogel, Victor M. Wiegant, Peter Hoogerhout, Dick J. De Wildt, Dirk H.G. Versteeg

Journal:

Brain Research

Année:

1996

Langue:

english

Fichier:

PDF, 1.75 MB

english, 1996

Tailor-made drug treatment for children: Creation of an infrastructure for data-sharing and population PK–PD modeling

Ibrahim Ince, Saskia N. de Wildt, Dick Tibboel, Meindert Danhof, Catherijne A.J. Knibbe

Journal:

Drug Discovery Today

Année:

2009

Langue:

english

Fichier:

PDF, 195 KB

english, 2009

The effect of inflammation on drug metabolism: a focus on pediatrics

Nienke J. Vet, Matthijs de Hoog, Dick Tibboel, Saskia N. de Wildt

Journal:

Drug Discovery Today

Année:

2011

Langue:

english

Fichier:

PDF, 239 KB

english, 2011

In vivo pertussis toxin treatment reduces contraction of rat resistance arteries but not that of mouse trachea

Cornelia E. van Meijeren, Wim Vleeming, Ton van de Kuil, Javotte Manni, Diane Kegler, Coenraad F.M. Hendriksen, Dick J. de Wildt

Journal:

European Journal of Pharmacology

Année:

2004

Langue:

english

Fichier:

PDF, 352 KB

english, 2004

Pertussis toxin-induced histamine sensitisation: an aspecific phenomenon independent from the nitric oxide system?

Cornelia E. van Meijeren, Wim Vleeming, Ton van de Kuil, Anne-Loes Gerards, Coenraad F.M. Hendriksen, Dick J. de Wildt

Journal:

European Journal of Pharmacology

Année:

2004

Langue:

english

Fichier:

PDF, 560 KB

english, 2004

Pertussis toxin relaxes small arteries with no vascular lesions or vascular smooth muscle cell injury

Cornelia E. van Meijeren, Wim Vleeming, Jan A.M.A. Dormans, Ton van de Kuil, Antoon Opperhuizen, Coenraad F.M. Hendriksen, Dick J. de Wildt

Journal:

Experimental and Toxicologic Pathology

Année:

2004

Langue:

english

Fichier:

PDF, 570 KB

english, 2004

Rat middle cerebral artery occlusion by an intraluminal thread compromises collateral blood flow

Richard C.G Herz, Carina M Kasbergen, Berend Hillen, Dirk H.G Versteeg, Dick J de Wildt

Journal:

Brain Research

Année:

1998

Langue:

english

Fichier:

PDF, 189 KB

english, 1998

Collateral hemodynamics after middle cerebral artery occlusion in Wistar and Fischer-344 rats

Richard C.G Herz, Berend Hillen, Dirk H.G Versteeg, Dick J De Wildt

Journal:

Brain Research

Année:

1998

Langue:

english

Fichier:

PDF, 388 KB

english, 1998

Melanocortins and cardiovascular regulation

Dirk H.G. Versteeg, Patricia Van Bergen, Roger A.H. Adan, Dick J. De Wildt

Journal:

European Journal of Pharmacology

Année:

1998

Langue:

english

Fichier:

PDF, 368 KB

english, 1998

Respiratory Arrest as Main Determinant of Toxicity due to Overdose with Different β–Blockers in Rats

Johanna Langemeijer, Dick de Wildt, Gerard de Groot, Bart Sangster

Journal:

Basic & Clinical Pharmacology & Toxicology

Année:

1985

Langue:

english

Fichier:

PDF, 362 KB

english, 1985

Inhibition of Iron-Dependent and Ischemia-Induced Brain Damage by the α-Tocopherol Analogue MDL 74,722

H.Bernardus van der Worp, Craig E. Thomas, L.Jaap Kappelle, Wherly P. Hoffman, Dick J. de Wildt, Peter R. Bär

Journal:

Experimental Neurology

Année:

1999

Langue:

english

Fichier:

PDF, 128 KB

english, 1999

Synchronism of pressor response and grooming behavior in freely moving, conscious rats following intracerebroventicular administration of ACTH/MSH-like peptides

Dirk H.G. Versteeg, Wouter J. Florijn, Anthony J.G.D. Holtmaat, Willem Hendrik Gispen, Dick J. De Wildt

Journal:

Brain Research

Année:

1993

Langue:

english

Fichier:

PDF, 516 KB

english, 1993

Severe impairment of cholinergic and adrenergic responsiveness in Bordetella pertussis vaccinated rats

Dick J. De Wildt, Johan G. Kreeftenberg, Frans P. Nijkamp

Journal:

European Journal of Pharmacology

Année:

1982

Langue:

english

Fichier:

PDF, 144 KB

english, 1982

Disturbed adrenergic regulation of coronary flow in the guinea-pig heart after endotoxin

Dicky Van Heuven-Nolsen, Dick J. De Wildt, Frans P. Nijkamp

Journal:

European Journal of Pharmacology

Année:

1985

Langue:

english

Fichier:

PDF, 489 KB

english, 1985

Effects of dexamethasone and indomethacin on the vascular β2-adrenolytic action of pertussis toxin in rats; A prostaglandin-mediated phenomenon

Dick J. De Wildt, Eline M. Van Der Beek, Yeb De Jong, Frans P. Nijkamp, Johan G. Kreeftenberg

Journal:

European Journal of Pharmacology

Année:

1985

Langue:

english

Fichier:

PDF, 462 KB

english, 1985

Vascular β-adrenoceptor blocking activity of endotoxin and pertussis toxin from Bordetella pertussis in rats

Dick J. De Wildt, Yeb De Jong, Frans P. Nijkamp, Johan G. Kreeftenberg

Journal:

European Journal of Pharmacology

Année:

1986

Langue:

english

Fichier:

PDF, 457 KB

english, 1986

Further study of possible direct vascular actions of indapamide in the conduit and renal arteriolar vessels of spontaneously hypertensive rats

Dick J. De Wildt, Anthoni Van de Kuil, Feddo C. Hillen, Gerard De Groot

Journal:

European Journal of Pharmacology

Année:

1988

Langue:

english

Fichier:

PDF, 571 KB

english, 1988

In vivo β2-adrenoceptor hyporesponsiveness in the cardiovascular system of the pig after Bordetella pertussis

Dicky Van Heuven-Nolsen, Erik Schoute, Pieter D. Verdouw, Dick J. De Wildt, Frans P. Nijkamp

Journal:

European Journal of Pharmacology

Année:

1989

Langue:

english

Fichier:

PDF, 493 KB

english, 1989

Carsdiovascular responses to milrinone in pertussis toxin-pretreated pithed rats

Ruud Verrijk, Dick J. De Wildt, Hans H. Van Rooij, Johan Wemer, Arijan J. Porsius

Journal:

European Journal of Pharmacology

Année:

1990

Langue:

english

Fichier:

PDF, 893 KB

english, 1990

Modulation by pertussis toxin of salbutamol- and arecoline-induced effects in the isolated heart and aorta of the rat

Wim Vleeming, Johan Wemer, Jan Riezebos, Jan G.C. Van Amsterdam, Dick J. De Wildt, Arijan J. Porsius

Journal:

European Journal of Pharmacology

Année:

1993

Langue:

english

Fichier:

PDF, 674 KB

english, 1993

The hemodynamic effects of γ2-melanocyte-stimulating hormone and related melanotropins depend on the arousal potential of the rat

Dick J. De Wildt, Harm Krugers, Carina M. Kasbergen, Henk De Lang, Dirk H.G. Versteeg

Journal:

European Journal of Pharmacology

Année:

1993

Langue:

english

Fichier:

PDF, 722 KB

english, 1993

Effects of nimodipine on sciatic nerve blood flow and vasa nervorum responsiveness in the diabetic rat

Arnoud C. Kappelle, Geert J. Biessels, Theo Van Buren, D. Willem Erkelens, Dick J. De Wildt, Willem H. Gispen

Journal:

European Journal of Pharmacology

Année:

1993

Langue:

english

Fichier:

PDF, 753 KB

english, 1993

Cardiovascular effects of γ-MSH/ACTH-like peptides: structure-activity relationship

Patricia Van Bergen, Paul M.L. Janssen, Peter Hoogerhout, Dick J. De Wildt, Dirk H.G. Versteeg

Journal:

European Journal of Pharmacology

Année:

1995

Langue:

english

Fichier:

PDF, 773 KB

english, 1995

Presynaptic deficit of sympathetic nerves: a cause for disturbed sciatic nerve blood flow responsiveness in diabetic rats

Theo Van Buren, Carina M. Kasbergen, Willem H. Gispen, Dick J. De Wildt

Journal:

European Journal of Pharmacology

Année:

1996

Langue:

english

Fichier:

PDF, 649 KB

english, 1996

The effects of γ2-melanocyte-stimulating hormone and nimodipine on cortical blood flow and infarction volume in two rat models of middle cerebral artery occlusion

Richard C.G. Herz, Dick J. De Wildt, Dirk H.G. Versteeg

Journal:

European Journal of Pharmacology

Année:

1996

Langue:

english

Fichier:

PDF, 1.13 MB

english, 1996

A disturbed macrocirculatory supply as a determinant for a reduced sciatic nerve blood flow in diabetic rats

Theo Van Buren, Arnoud C Kappelle, Carina M Kasbergen, Willem H Gispen, Dick J De Wildt

Journal:

European Journal of Pharmacology

Année:

1996

Langue:

english

Fichier:

PDF, 146 KB

english, 1996

Structure-activity analysis for the effects of γ-MSH/ACTH-like peptides on cerebral hemodynamics in rats

Patricia Van Bergen, Jan G.M. Van Der Vaart, Carina M. Kasbergen, Dirk H.G. Versteeg, Dick J. De Wildt

Journal:

European Journal of Pharmacology

Année:

1996

Langue:

english

Fichier:

PDF, 1.05 MB

english, 1996

The effect of pertussis toxin and whole-cell pertussis vaccine on haemodynamics and autonomic responsiveness in the rat depends on route of administration and age

Jan G.C. van Amsterdam, Jan-Dirk te Biesebeek, Ton van de Kuil, Jan-Willem van der Laan, Johan Wemer, Dick J. de Wildt, Wim Vleeming

Journal:

Vaccine

Année:

1998

Langue:

english

Fichier:

PDF, 768 KB

english, 1998

Repeated administration of whole-cell and acellular pertussis vaccines affects haemodynamics and autonomic responsiveness

Jan G.C. van Amsterdam, Jan-Dirk te Biesebeek, Ton van de Kuil, Jan-Willem van der Laan, Dick J. de Wildt, Wim Vleeming

Journal:

Vaccine

Année:

1998

Langue:

english

Fichier:

PDF, 872 KB

english, 1998

An evaluation of derived aortic flow parameters as indices of myocardial contractility in rats

Dick J. de Wildt, Bart Sangster

Journal:

Journal of Pharmacological Methods

Année:

1983

Langue:

english

Fichier:

PDF, 751 KB

english, 1983

The effect of the adrenocorticotropin-(4-9) analogue, ORG 2766, and of dizolcipine (MK-801) on infarct volume in rat brain

Richard C.G Herz, Carina M Kasbergen, Dirk H.G Versteeg, Dick J De Wildt

Journal:

European Journal of Pharmacology

Année:

1998

Langue:

english

Fichier:

PDF, 120 KB

english, 1998

Geriatric pharmacology and pharmacotherapy education for health professionals and students: a systematic review

Keijsers, Carolina J. P. W., van Hensbergen, Larissa, Jacobs, Lotte, Brouwers, Jacobus R. B. J., de Wildt, Dick J., ten Cate, Olle Th. J., Jansen, Paul A. F.

Journal:

British Journal of Clinical Pharmacology

Année:

2012

Langue:

english

Fichier:

PDF, 1.26 MB

english, 2012

ACE Inhibitor-Induced Angioedema

Dr Wim Vleeming, Jan G. C. van Amsterdam, Bruno H. Ch. Stricker, Dick J. de Wildt

Journal:

Drug Safety

Année:

1998

Langue:

english

Fichier:

PDF, 178 KB

english, 1998

Daily interruption of sedation in critically ill children: study protocol for a randomized controlled trial

Vet, Nienke J, de Wildt, Saskia N, Verlaat, Carin WM, Knibbe, Catherijne AJ, Mooij, Miriam G, Hop, Wim CJ, van Rosmalen, Joost, Tibboel, Dick, de Hoog, Matthijs

Journal:

Trials

Année:

2014

Langue:

english

Fichier:

PDF, 229 KB

english, 2014

Evidence-Based Morphine Dosing for Postoperative Neonates and Infants

Krekels, Elke H. J., Tibboel, Dick, de Wildt, Saskia N., Ceelie, Ilse, Dahan, Albert, van Dijk, Monique, Danhof, Meindert, Knibbe, Catherijne A. J.

Journal:

Clinical Pharmacokinetics

Année:

2014

Langue:

english

Fichier:

PDF, 384 KB

english, 2014

Effect of hypothermia and extracorporeal life support on drug disposition in neonates

Wildschut, Enno D., de Wildt, Saskia N., Mâthot, Ron A.A., Reiss, I.K.M., Tibboel, Dick, Van den Anker, John

Journal:

Seminars in Fetal and Neonatal Medicine

Année:

2013

Langue:

english

Fichier:

PDF, 152 KB

english, 2013

Structured Pharmaceutical Analysis of the Systematic Tool to Reduce Inappropriate Prescribing Is an Effective Method for Final-Year Medical Students to Improve Polypharmacy Skills: A Randomized Controlled Trial

Keijsers, Carolina J. P. W., van Doorn, Adriaan B. D., van Kalles, Anouk, de Wildt, Dick J., Brouwers, Jacobus R. B. J., van de Kamp, Henrieke J., Jansen, Paul A. F.

Journal:

Journal of the American Geriatrics Society

Année:

2014

Langue:

english

Fichier:

PDF, 109 KB

english, 2014

Calcium Interferes with the Cardiodepressive Effects of Beta-Blocker Overdose in Isolated Rat Hearts

Langemeijer, Johanna, de Wildt, Dick, de Groot, Gerard, Sangster, Bart

Journal:

Clinical Toxicology (Informa Healthcare)

Année:

1986

Langue:

english

Fichier:

PDF, 828 KB

english, 1986